Lol. I’ve seen hot dogs sell here for US$13 (after conversion). The US doesn’t understand how cheap their food is, even with inflation. The minimum wage for adults is USD$15.40 though (again converted) and we don’t have “but it’s OK they get tips so we don’t have to pay them more than $2” shenanigans.

Fuck that paywall, but again the problem is largely how underpaid and exploited people are, not how much hot dogs have increased in price.

I appreciate you

1 patient, T2 since mid-30s and now 59, had kidney transplant 2017 after end-stage diabetic nephropathy and fucked glucose control since 2019. The successful cells were endoderm stem cells from him cultivated by mice they injected with his PBMCs that they then made diabetic. So not from cadavers (except mouse cadaver i guess), which is the actual new part here. Intrahepatic implant, and cells from unrelated donor failed that were embedded at the same time. His personalised mouse-donor cells worked well enough to take him off insulin 3 months later.

Wu, J., Li, T., Guo, M. et al. Treating a type 2 diabetic patient with impaired pancreatic islet function by personalized endoderm stem cell-derived islet tissue. Cell Discov 10, 45 (2024).

It’s good news, but you’re entirely correct that the article missed the point entirely. Thanks for the crash course in islet cell therapy!

Looming? Sudan is past the looming stage. When do known verified atrocities reach “current reality” status?

I once looked at a job listing for something with very specialist technical knowledge in specific programming areas, for a Japanese company based in Tokyo (pre-covid so remote wasn’t really a thing yet). Pretty niche stuff and needed at least basic Japanese language skills too, so I assumed it would pay ok - even if it wasn’t good or great in comparison with jobs where i was.

After conversion it worked out to be around USD$40k a year, which is probably just over 1/3 of what it would pay at minimum elsewhere. More like 1/4 or less for Silicon Valley type locations, but the rent for a tiny Tokyo shoebox is about the same price even if food is a cheaper. There was no way I was applying for that.

It isn’t just about a weak yen, it’s much more about hugely underpaying people.

It annoyed me that I couldn’t see the whole statue. It’s just a statue of the local general but another part of the inscription was also interesting:

THE CONFEDERATE SOLDIER WON AND IS ENTITLED TO THE ADMIRATION OF ALL WHO LOVE HONOR, AND LIBERTY.

Uh huh. From a monument built 50 years after the war ended. Physical copium.

It starts before birth. Low socio-economic status affects the health of pregnant people, which in turn has consequences for foetal development. Stress is a big trigger for various latent congenital issues, and that’s one reason climate change is going to result in increased rates of disease.

Not just a defense witness, a former federal prosecutor. A judge had to tell a former federal prosecutor “And then if you don’t like my ruling, you don’t give me side eye and you don’t roll your eyes.” like he was a pouty teenager.

There’s a person who has been living a mostly normal life with 90% of his brain missing. Perhaps we could just re-examine society’s ableism and how we design our systems of government to allow single points of failure instead? RFK Jr. has terrible opinions, but also had them before having a literal brain worm.

Dennett taught me how to find common ground with very different people in discussions which might otherwise be heated arguments. I was lucky enough to see one of his talks some years ago, and his work and methods are something I frequently think about even today. His writing style was playful and accessible, but it paled in comparison to his presentation which really demonstrated his abundant charisma. His passing is truly a huge loss in a world that increasingly needs his teachings. My condolences to his family and the communities he fostered.

Vale, Daniel C. Dennett. I hope I can continue to do even a shred of justice to your contributions.

Edit with link: Dennett (somewhat accidentally) created a community for interdenominational Christian clergy who are also secret atheists. It started with a research paper with interviews and some analysis of their similar/different experiences. Ignore the abstract if academic language isn’t your thing, the rest of the paper is a much easier and interesting read:

Dennett, D. C., & LaScola, L. (2010). Preachers Who are Not Believers. Evolutionary Psychology, 8(1), 122-150

very good mental healthcare

No, it’s just better than other places. It’s overstressed, underprioritised, acute-focussed and failing the population at large. Better than the US, even exponentially, doesn’t mean good.

Switching to what alliance? It’s not like they’re going to join BRICS.

I’m glad she has finally been acquitted but I am so sorry that she ever had to go through any of this

I finally gave in and watched it after multiple independent recommendations from people who had strong educated opinions on quality nuanced literature and media. The last series sort of declined a bit, but overall I was in no way disappointed. It was exceptionally well done, and importantly for me, not too watered down with tired tropes, stereotyped single dimensional characters, painfully predictable plots and neatly tidied moral threads.

I mean, there were definitely some, but, it’s TV. It holds up extremely well even with age.

For sure, but insults are just (nicely crafted in this case) words, and unless the insulter is in a certain position, they ultimately don’t affect much. It’s not like Simon’s statement is going to change Baltimore policy or shipping or things for the citizens, or Greene’s actions. And it’s not like Greene will be able to make funding decisions about Baltimore or declare war on the city.

Like, I enjoy some dramatic shit-slinging, but I wish “news” were more about objective things happening than someone expressing an opinion on social media that doesn’t have any obvious real consequences for anyone.

I don’t consider a TV producer insulting a (obviously terrible) politician to be news, but I do enjoy this particular insult. It’s nicely crafted. It’s a pity he continues to use Twitter.

Is that a forehead whisker? Is he unhappy about being a unicorn, or are you just not being prompt enough about food time?

This picture is my life goal. Content, comfortable and safe snoozing. Give winter a gentle pat for me, I wouldn’t want to wake them up.

Sounds like we had the same programmers. I feel you, Kairos.

In what way? The RNC will be funnelling cash before the election, and nothing has been done about Trump beyond some civil suits since his presidency. What has happened to make you think his cash flow has been restricted enough to prevent churning new loans that he won’t pay? He’s been doing it his entire life.