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Joined 1 year ago
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Cake day: June 13th, 2023

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  • This would be terrible business if any pharma worked this way. The vast majority of potential treatments fail either in the lab or in early phase trials. It is not very likely that’d you’d be able to on-demand develop a novel treatment for symptoms before one of your competitors figured out your already-discovered cure. That would be unless you patented the cure, but by the time you spent years developing a new symptom-only treatment and testing it through each phase, you’d have a few years at best before your exclusivity on the cure patent expires and thus your treatment becomes worthless.

    Pharmas are run by the same short-sighted wall streeters as every other corporation. Actually successfully executing this sort of long-term plan would require thinking further ahead than a few quarters, which they are not capable of doing. A new cure is a big stock boost now that they could never resist.






  • I forget the specifics and who came up with it, but: pick an amount you haven’t written before. Then, write that much without looking back. If you can set your word processor to only keep your current line visible, even better. Once you’ve written that many paragraphs or pages, do a fast edit. Use a timer so you can’t linger. Then write that much again with the same strategy. After 3-5 times, do a more thorough edit of the whole thing.

    It’s not necessarily how you always want to write, but it can help getting over that initial confidence block as an exercise.




  • Great, and where local is the best choice they should do that. But nobody can seriously argue that reducing the ability of government to shop around for the best cost/quality balance is a good thing. It’s not like the only options are buy everything American or everything from China. I’d like qualified experts making that decision, not legislators.

    You create bad incentives if you artificially reduce competition like this. Not every good or service will have tons of American choices, so you end up with a handful of companies who know the government has no other choice.




  • This is a notoriously difficult thing to prove out either way in data, and I’m sure it varies situationally.

    The Mariel Boatlift natural experiment did not demonstrate a decrease in wages or increase in unemployment. It makes sense: immigrants both work and consume (i.e., create demand). Unless every immigrant happens to work in the same industry/union, the sum total of immigrants may create demand for labor equal to or greater than they fill.

    It also may have the impact you’re suggesting. But it doesn’t have to be zero sum. And, understandably, people only remember when they lost a job potentially tied to immigrant labor. Nobody asks if the job they’re applying to was created due to demand immigrants added to the economy (and how could a company know that?).





  • Two points about R&D costs:

    First, they aren’t just trying to make up what they spent on this treatment, but others that failed during research/trials. There’s a lot of them the general public will never hear about, and pharmas generally don’t like to bring attention to their failures. Part of that is many shareholders are morons who don’t understand how science works.

    Second, the costs can get fuzzier for larger companies who in-house much of the R&D process, since the costs get shared among many programs. Properly attributing spend in that case can be a serious challenge.

    All that said, they’ve clearly seen an opportunity to rake it in with this trendy drug and are charging way more than they need to.