I’m thinking I would go with either, “swing it, baby” or “right on, sister!”
So, like-
“Mr. Nartik, set course for Tau Alpha III. Warp six.”
“Course laid in, sir.”
“Right on, sister!”
This would be the 23rd or 24th century gender-neutral form of the word sister, obviously.
I’m Australian so I’m legally obligated to go with “Fukken fang it carrnts!”